Pamela J Shaw Selected Research

Nuclear RNA

10/2021	SRSF1-dependent inhibition of C9ORF72-repeat RNA nuclear export: genome-wide mechanisms for neuroprotection in amyotrophic lateral sclerosis.
12/2011	Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology.

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Pamela J Shaw Research Topics

Disease

76	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 10/2022 - 06/2002
18	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 08/2005
14	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2022 - 09/2003
12	Disease Progression 01/2022 - 10/2002
7	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 03/2006
7	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 06/2010
6	Frontotemporal Dementia (Semantic Dementia) 12/2016 - 03/2010
5	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 10/2013
5	Dementia (Dementias) 01/2021 - 05/2007
4	Proteostasis Deficiencies 01/2021 - 03/2012
4	Deglutition Disorders (Dysphagia) 03/2016 - 03/2013
4	Hypoxia (Hypoxemia) 02/2015 - 01/2006
3	Hereditary Spastic Paraplegia 01/2022 - 12/2003
3	Parkinson Disease (Parkinson's Disease) 10/2018 - 08/2013
3	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 01/2018 - 03/2010
3	TDP-43 Proteinopathies 01/2016 - 10/2014
3	Cognitive Dysfunction 12/2015 - 06/2015
3	Death (Near-Death Experience) 10/2013 - 04/2012
3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 09/2013 - 05/2010
3	Spastic Paraparesis 12/2003 - 06/2003
2	Infections 03/2022 - 01/2015
2	Neuroinflammatory Diseases 10/2020 - 05/2013
1	Muscular Diseases (Myopathy) 05/2022
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Channelopathies 11/2020
1	Paralysis (Palsy) 11/2020
1	Myotonia Congenita (Thomsen Disease) 11/2020
1	Injection Site Reaction 09/2020
1	Diabetes Mellitus 01/2020
1	Embolism (Embolus) 01/2020
1	Leukocytosis (Pleocytosis) 01/2020
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2020
1	Starvation 12/2019
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2019

Drug/Important Bio-Agent (IBA)

19	Biomarkers (Surrogate Marker)IBA 05/2022 - 05/2013
12	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2006
12	Superoxide Dismutase-1IBA 09/2018 - 06/2002
7	RNA (Ribonucleic Acid)IBA 01/2021 - 05/2013
6	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2018 - 03/2010
6	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 08/2005
4	MicroRNAs (MicroRNA)IBA 01/2017 - 10/2013
4	Superoxide DismutaseIBA 01/2014 - 02/2011
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2010 - 05/2005
4	SpastinIBA 07/2009 - 06/2003
3	EnzymesIBA 01/2022 - 11/2015
3	NAD (NADH)IBA 01/2021 - 12/2006
3	Messenger RNA (mRNA)IBA 12/2019 - 10/2014
3	Adenine FDA LinkGeneric 12/2019 - 01/2016
3	Mitochondrial DNA (mtDNA)IBA 04/2007 - 03/2006
2	Creatine Kinase (Creatine Phosphokinase)IBA 10/2022 - 01/2022
2	LipidsIBA 01/2022 - 01/2015
2	Nuclear RNAIBA 10/2021 - 12/2011
2	tau Proteins (tau Protein)IBA 01/2021 - 12/2015
2	Amyloid beta-PeptidesIBA 01/2021 - 12/2015
2	Interleukin-2 (IL2)IBA 01/2021 - 09/2020
2	Inosine FDA Link 01/2021 - 01/2019
2	Amyloid (Amyloid Fibrils)IBA 04/2020 - 01/2015
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 02/2020 - 12/2019
2	GlycosyltransferasesIBA 01/2020 - 01/2019
2	polyglutamineIBA 01/2020 - 01/2016
2	Niacinamide (Nicotinamide)FDA LinkGeneric 12/2019 - 01/2019
2	Lithium Carbonate (Eskalith)FDA LinkGeneric 10/2017 - 09/2011
2	Riluzole FDA LinkGeneric 01/2016 - 06/2010
2	ProgranulinsIBA 03/2014 - 03/2010
2	UbiquitinIBA 09/2012 - 05/2007
2	Glutamic Acid (Glutamate)FDA Link 08/2004 - 10/2002
1	InterferonsIBA 03/2022
1	Untranslated Regions (Untranslated Region)IBA 01/2022
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2022
1	Ferritins (Ferritin)IBA 01/2022
1	BradykininIBA 01/2022
1	chitotriosidaseIBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	Isoleucine (L-Isoleucine)FDA Link 01/2022
1	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2022
1	CeramidesIBA 12/2021
1	Protein AggregatesIBA 01/2021
1	ProteomeIBA 01/2021
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 01/2021
1	Cysteine (L-Cysteine)FDA Link 01/2021
1	Ion Channels (Ion Channel)IBA 11/2020
1	SodiumIBA 11/2020
1	Histone Deacetylases (Histone Deacetylase)IBA 10/2020
1	aldesleukin (Proleukin)FDA Link 09/2020
1	tofersenIBA 01/2020
1	Advanced Glycation End ProductsIBA 01/2020
1	Pharmaceutical PreparationsIBA 12/2019
1	Adenosine (Adenocard)FDA LinkGeneric 12/2019
1	FructoseIBA 12/2019
1	GlycogenIBA 12/2019
1	Adenosine DeaminaseIBA 01/2019
1	Phosphotransferases (Kinase)IBA 11/2018
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 10/2018

Therapy/Procedure

12	Therapeutics 12/2021 - 09/2009
10	Noninvasive Ventilation 01/2016 - 02/2006
4	Gastrostomy 03/2016 - 12/2010
4	Lasers (Laser) 10/2014 - 08/2005
3	Precision Medicine 01/2022 - 01/2017
2	Orthotic Devices (Orthosis) 01/2018 - 07/2016